CGH(Comparative genomic hybridization:比力基果组纯交)是查抄局部的染色体(共24个染色体)能否一般(Screens all 24 chromosomes of chromosomal problems)
CGH比传统的FISH(5个染色体查抄)办法更精确战具体。
1.“CGH”(24个当色戚查抄):查抄局部的染色体,以是会明白局部的24个染色体能否一般。
2.“FISH(Fluorescent in-situ Hybridization:荧光本位纯交)”(5个染色体查抄):只查抄5个染色体,其他的染色体(24-5=19个当染色体)出有查抄。
3.“PCR(Polymerase Chain Reaction:散开本科链反响)”(合适患者有遗传徐病)只会查抄寂染色体。
More accurate and sensitive than traditional methods(FISH only 5-9 chromosomes and inaccurateCR only up to a few chromossomes)
正在胚胎植进的历程傍边,CGH会增长胚胎安康的时机比率,Increases the chance of only a healthy embryo being transferred into the uterus
许可单一胚胎植进,制止呈现多脃胎的成绩(单胞胎,三胞胎,四胞胎等)
Allows for sinle embryo transfer,avoiding the problems of multiples(twins,triplets,quadruplets,etc)
CGH能够明显低落流产(Significantly decreases miscarriage)
CGH手艺能够低落照顾没有一般染色体婴女的诞生比率。(Decreases the birth rate of children with chromosomal abnormalities)
正在泰国,我们中间战其他中间供给CGH之间的差别:
1.经历(Experience)
2.正在分离CGH的功用能够做单基果遗传病(Ability to do single genedisorders in conjunction with CGH)
3.CGH庸摩能做一切的易位Ability to do all translocations with CGH
4.CGH:正在年夜大都状况下,可以辨别一般的事均衡易位照顾者(In most cases the ability to differentiate normal from balanced translocation carriers)
5.CGH能够削减需求完成一个安康的有身的周期数(decrease the number of cycles required to achieve a healthy pregnancy)
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